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Logging this consistently, rather than estimating it, is the single biggest lever most people are missing

Another safety finding: exenatide is renally cleared, and there were cases of acute kidney injury in people with renal impairment or dehydration while on exenatide ( [108] )

Importantly, the concentration of lactate correlated with pain thresholds and pain intensity demonstrating a link between disturbed oxidative energy metabolism and chronic pain