Rat Beta-Arrestin-1, ARRB1 ELISA Kit, 96T Protein Expression Multiple alternatively spliced transcript variants
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Rat Beta-Arrestin-1, ARRB1 ELISA Kit, 96T Protein Expression Multiple alternatively spliced transcript variantsFunctions in regulating agonist mediated G protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta arrestins bind to the GPRK phosphorylated receptor and sterically preclude its coupling to the cognate G protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta arrestins target
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