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HNF1A Polyclonal Antibody, 20ul Biomatrix RAPGEF1 encodes a human guanine

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HNF1A Polyclonal Antibody, 20ul Biomatrix RAPGEF1 encodes a human guanineThe protein encoded by this gene is a transcription factor required for the expression of several liver specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5' GTTAATNATTAAC 3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different

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Description

RAPGEF1 encodes a human guanine nucleotide exchange factor

Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex

The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA

The protein encoded by this gene contains a formin homology 2 domain and has high sequence identity to the mouse Wbp3 protein

This gene encodes a protein belonging to the guanine nucleotide exchange factor family

HNF1A Polyclonal Antibody, 20ul Biomatrix RAPGEF1 encodes a human guanineThe protein encoded by this gene is a transcription factor required for the expression of several liver specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5' GTTAATNATTAAC 3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different

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