XPO7 Polyclonal Antibody, 100ul Molecular Weight Markers Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants have been found| but the full-length nature of some variants has not been defined

The protein encoded by CXCR2 is a member of the G-protein-coupled receptor family

The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum

This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation

and also in the phagocytosis of complement coated particles

XPO7 Polyclonal Antibody, 100ul Molecular Weight Markers Multiple alternatively spliced transcript variantsThe transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin alpha beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS dependent protein import. RAN binding protein 16 is a member of