ATM Rabbit Polyclonal Antibody, 50ul[BT-AP06560] In vitro Assessment The protein is active alone

The protein is active alone or as a heteromultimeric assembly with TRPC1| TRPC3| and TRPC4

This protein possesses 3' to 5' exonuclease activity

SP3 (Sp3 transcription factor) belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes

Several alternatively spliced transcript variants of FKRP have been described

Mutations in this gene are associated with nonsyndromic progressive hearing loss

ATM Rabbit Polyclonal Antibody, 50ul[BT-AP06560] In vitro Assessment The protein is active aloneThe protein encoded by this gene belongs to the PI3 PI4 kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of