p53 Polyclonal Antibody, 20ul[BT-AP06825] Recombinant Protein Expression This G-protein coupled receptor stimulates

This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases

The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs)

Several transcript variants encoding two different isoforms have been found for this gene

Alternatively spliced transcript variants encoding multiple isoforms have been observed for ITCH

Negative regulator of ubiquitin like proteins 1 interacts with the product of the AIPL1 gene

p53 Polyclonal Antibody, 20ul[BT-AP06825] Recombinant Protein Expression This G-protein coupled receptor stimulatesTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.