IP3R-I Polyclonal Antibody, 20ul[BT-AP04603] Gloves CCR4-NOT transcription complex subunit 7

CCR4-NOT transcription complex subunit 7 encoded by CNOT7 binds to an anti-proliferative protein

The encoded protein is a putative acyltransferase and is most likely involved in the synthesis of di- or triacylglycerol

Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome

This protein was also reported to participate in the recruitment of tyrosine kinase SYK

is located approximately 25 kb away from CYP1A1 on chromosome 15

IP3R-I Polyclonal Antibody, 20ul[BT-AP04603] Gloves CCR4-NOT transcription complex subunit 7ITPR1 (inositol 1,4,5 trisphosphate receptor type 1) encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for ITPR1.