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Akt1 Polyclonal Antibody, 50ul[BT-AP00347] Vector Construction As is typical for genes

SKU: 11245780632

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Akt1 Polyclonal Antibody, 50ul[BT-AP00347] Vector Construction As is typical for genesThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

As is typical for genes encoding ribosomal proteins

suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis

The multiprotein complex serves to tranduce signals that involve changes in cell shape

while SNAP25 is present almost exclusively in the brain

Stress-activated kinase involved in tolerance to glucose starvation

Akt1 Polyclonal Antibody, 50ul[BT-AP00347] Vector Construction As is typical for genesThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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