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E2F-4/5 Polyclonal Antibody, 20ul RNA Synthesis Multiple transcript variants encoding different

SKU: 11405972911

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E2F-4/5 Polyclonal Antibody, 20ul RNA Synthesis Multiple transcript variants encoding differentE2F transcription factor 4 encoded by E2F4 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which

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Description

Multiple transcript variants encoding different isoforms have been found for this gene

Inactivating variants of this gene result in the recessive Lutheran null phenotype

The MYC binding protein encoded by MYCBP binds to the N-terminus of the oncogenic protein C-MYC

A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19

It influences cellular physiologic processes by regulating the expression of downstream target genes

E2F-4/5 Polyclonal Antibody, 20ul RNA Synthesis Multiple transcript variants encoding differentE2F transcription factor 4 encoded by E2F4 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which

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