IRGM Polyclonal Antibody, 100ul Drug Development and Evaluation and active when dephosphorylated at

and active when dephosphorylated at this site

Transcription of this gene is highly inducible in response to many cytokines and hormones

It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes

The enzyme has widespread tissue expression and has a role in metabolism

Several alternatively spl

IRGM Polyclonal Antibody, 100ul Drug Development and Evaluation and active when dephosphorylated atThis gene encodes a member of the p47 immunity related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.