BMPER Polyclonal Antibody, 100ul Plasma The gene was found to

The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein

Defects in POU4F3 are the cause of non-syndromic sensorineural deafness autosomal dominant type 15

Three alternatively spliced transcript variants that encode different protein isoforms have been described

a subpopulation that does not interact with catenins

Summary:This gene belongs to the casein kinase 1 superfamily

BMPER Polyclonal Antibody, 100ul Plasma The gene was found toThis gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2 and BMP4 dependent osteoblast differentiation and BMP dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis.