14-3-3 Beta Polyclonal Antibody, 100ul[BT-AP00004] 3D Culture Two isoforms of DYRK2 have

Two isoforms of DYRK2 have been isolated

The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes

and binds specifically to MAP kinase kinase MAP2K1/MEK1

but the transcript sequences of some variants are not determined

The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes

14-3-3 Beta Polyclonal Antibody, 100ul[BT-AP00004] 3D Culture Two isoforms of DYRK2 haveYWHAZ (tyrosine 3 monooxygenase tryptophan 5 monooxygenase activation protein zeta) product belongs to the 14 3 3 family of proteins which mediate signal transduction by binding to phosphoserine containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin