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Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 20ul Palm Micro Centrifuges The protein encoded by this

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Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 20ul Palm Micro Centrifuges The protein encoded by thisATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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Description

The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex

This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction

or alternatively

These channels are assembled from 4 related subunits

Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p

Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 20ul Palm Micro Centrifuges The protein encoded by thisATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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