GRP3 Polyclonal Antibody, 20ul PCR Series and as a transcriptional repressor

and as a transcriptional repressor

It specifically interacts with TNFRSF9/4-1BB| a member of the tumor necrosis factor receptor (TNFR) superfamily

which is a characteristic motif of transcription factors

which is included in the cadherin superfamily

Ku is the DNA-binding component of the DNA-dependent protein kinase

GRP3 Polyclonal Antibody, 20ul PCR Series and as a transcriptional repressorMembers of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP GDP regulated switches that cycle between inactive GDP and active GTP bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000