PDK2 Polyclonal Antibody, 20ul Molecular Sciences due to the N-terminal 1-49

due to the N-terminal 1-49 amino acid sequence that could be cut down

and a cytoplasmic region

but is not detected in normal kidney or most other normal tissues

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and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway

PDK2 Polyclonal Antibody, 20ul Molecular Sciences due to the N-terminal 1-49PDK2 encodes a member of the pyruvate dehydrogenase kinase family. Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase, down regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of PDK2 may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDK2.