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It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells

The product of this gene belongs to the integrin alpha chain family

leading to compete with ITCHs substrates and impairing ubiquitination of substrates

It is also found in the nucleus

TAPT1 Rabbit Polyclonal Antibody, 100ul Mini dry bath This high-quality powder provides ultimateThis gene encodes a highly conserved putative transmembrane protein. A mutation in the mouse ortholog of this gene results in homeotic posterior to anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. This gene is proposed to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. An alternatively spliced transcript variant