ZPR1 Rabbit Polyclonal Antibody, 20ul Glassware SLC22A18 is imprinted

SLC22A18 is imprinted

hMCLC-3 and hMCLC-4

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This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU)

Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria

ZPR1 Rabbit Polyclonal Antibody, 20ul Glassware SLC22A18 is imprintedThe protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene.