CPNS2 Polyclonal Antibody, 20ul Vector Construction The MAPKKK5 protein phosphorylates and

The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1| MAPKK4) in vitro| and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells

Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported

Isoform 2 does not interact with CUL4A but still binds to RBX1

The protein encoded by PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1) belongs to the ser/thr protein kinase family

The encoded protein is unique in that its C-terminus is derived from CHARLIE8 transposable element sequence

CPNS2 Polyclonal Antibody, 20ul Vector Construction The MAPKKK5 protein phosphorylates andCalcium regulated non lysosomal thiol protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.,Contains 4 EF hand domains.,subcellular location: Translocates to the plasma membrane upon calcium binding.,subunit: Heterodimer of a large