S22AC Rabbit Polyclonal Antibody, 100ul Protein Expression The encoded preproprotein is proteolytically

The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor

GDF5 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

as it contains characteristic adjacent cysteine residues

it can function as a co-repressor of androgen-responsive gene expression

particularly during embryonic development

S22AC Rabbit Polyclonal Antibody, 100ul Protein Expression The encoded preproprotein is proteolyticallyThe protein encoded by this gene is a member of the organic anion transporter (OAT) family and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate hyperuricemia is associated with increased incidences of gout and mutations in this gene cause renal hypouricemia type 1. Alternative splicing