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LKB1 Polyclonal Antibody, 20ul[BT-AP05038] Sealing Film This gene product interacts with

SKU: 13994655462

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LKB1 Polyclonal Antibody, 20ul[BT-AP05038] Sealing Film This gene product interacts withSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

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Description

This gene product interacts with Parkin and is involved in juvenile Parkinson disease

this protein contains transducin-like repeats

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and G-protein coupled amine receptor activity

Tissue-specific utilization of alternative polyA-signal has been described in literature

Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers

LKB1 Polyclonal Antibody, 20ul[BT-AP05038] Sealing Film This gene product interacts withSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

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