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CD155 Polyclonal Antibody, 100ul Peptide Modification Mutations in this gene are

SKU: 14055761462

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CD155 Polyclonal Antibody, 100ul Peptide Modification Mutations in this gene areThe poliovirus receptor encoded by PVR is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex 1 DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript

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Description

Mutations in this gene are associated with adermatoglyphia

Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling

This protein is expressed in pro-B-cells and is thought to play a role in their differentiation

Homologs of mammalian mucolipins exist in Drosophila and C

Polymorphisms in this protein appear to be tissue specific and influence protease targeting

CD155 Polyclonal Antibody, 100ul Peptide Modification Mutations in this gene areThe poliovirus receptor encoded by PVR is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex 1 DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript

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