ORCTL2 Polyclonal Antibody, 50ul Cellular Cultivation & Health Management The CPC complex has essential

The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly

The encoded protein has been shown to interact with the cancer developmental regulators SMAD2

This protein plays important roles in the paracellular cation barrier of the distal renal tubule

ranging from neonatal adrenoleukodystrophy to Zellweger syndrome

These proteins function either as transcriptional activators or repressors of numerous genes

ORCTL2 Polyclonal Antibody, 50ul Cellular Cultivation & Health Management The CPC complex has essentialSLC22A18 is one of several tumor suppressing subtransferable fragments located in the imprinted gene domain of 11p15. , an important tumor suppressor gene region. Alterations in this region have been associated with the Beckwith Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. SLC22A18 is imprinted, with preferential expression from the maternal allele. Mutations in SLC22A18 have been