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ZC3H13 Polyclonal Antibody, 50ul Cell Culture Aconitases are iron-sulfur proteins that

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ZC3H13 Polyclonal Antibody, 50ul Cell Culture Aconitases are iron-sulfur proteins thatThe zinc finger CCCH domain containing protein 13 (ZC3H13) is a 1668 amino acid protein that contains one C3H1 type zinc finger. ZC3H13 is phosphorylated upon DNA damage, most likely by ATM or ATR. Two isoforms of ZC3H13 exists as a result of alternative splicing events. The gene encoding ZC3H13 maps to chromosome 13, which contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer

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Description

Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate

disease:Defects in STAT3 are the cause of hyperimmunoglobulin E recurrent infection syndrome autosomal dominant (AD-HIES)

The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase

In both human and mouse

The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor

ZC3H13 Polyclonal Antibody, 50ul Cell Culture Aconitases are iron-sulfur proteins thatThe zinc finger CCCH domain containing protein 13 (ZC3H13) is a 1668 amino acid protein that contains one C3H1 type zinc finger. ZC3H13 is phosphorylated upon DNA damage, most likely by ATM or ATR. Two isoforms of ZC3H13 exists as a result of alternative splicing events. The gene encoding ZC3H13 maps to chromosome 13, which contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer

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