RXRB Polyclonal Antibody, 100ul Custom DNA Oligos and a short C-terminal cytoplasmic

and a short C-terminal cytoplasmic tail

and is expressed in tumors of various histological types

The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase

The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin

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RXRB Polyclonal Antibody, 100ul Custom DNA Oligos and a short C-terminal cytoplasmicThis gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6.