p300 (Acetyl Lys1542) Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Mutations in this gene are

Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease)

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and lower expression in lung

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase

The enzymatic activity is under the control of several hormones

p300 (Acetyl Lys1542) Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Mutations in this gene areThis gene encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co activator of HIF1A (hypoxia inducible factor 1