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p16 Polyclonal Antibody, 100ul[BT-AP06744] Endonucleases & Exonucleases Ubiquitin-like molecules (UBLs)

SKU: 15586574653

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p16 Polyclonal Antibody, 100ul[BT-AP06744] Endonucleases & Exonucleases Ubiquitin-like molecules (UBLs)CDKN2A (cyclin dependent kinase inhibitor 2A) generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an

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Description

Ubiquitin-like molecules (UBLs)

The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells

The soluble isoforms are associated with the onset of pre-eclampsia

Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females

it may regulate epithelial cell migration (PubMed: 23902688)

p16 Polyclonal Antibody, 100ul[BT-AP06744] Endonucleases & Exonucleases Ubiquitin-like molecules (UBLs)CDKN2A (cyclin dependent kinase inhibitor 2A) generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an

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