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UN13D Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis These glycosylases initiate the first

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UN13D Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis These glycosylases initiate the first

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Description

These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al

Defects in this gene are a cause of several syndromes

Also involved in negative regulation of the cell cycle

The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport

It has histone deacetylase activity and represses transcription when tethered to a promoter

UN13D Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis These glycosylases initiate the first

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