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PP4R1 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging and have a critical role

SKU: 16264473923

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PP4R1 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging and have a critical roleThis gene encodes one of several alternate regulatory subunits of serine threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.

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Description

and have a critical role in the maturation of

An important paralog of this gene is HSH2D

An allelic polymorphism in FCGR2C results in both coding and non-coding variants

hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19

this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter

PP4R1 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging and have a critical roleThis gene encodes one of several alternate regulatory subunits of serine threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.

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