USP16 Polyclonal Antibody, 100ul Serological Pipets The protein encoded by this

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily

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Involved in suppression of IL13-induced STAT6 phosphorylation

Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients

The core complex possesses DNA-dependent ATPase activity

USP16 Polyclonal Antibody, 100ul Serological Pipets The protein encoded by thisUSP16 encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.