p53 Polyclonal Antibody, 20ul[BT-AP06818] 3D Culture Erb-b2 receptor tyrosine kinase 2

Erb-b2 receptor tyrosine kinase 2 has no ligand binding domain of its own and therefore cannot bind growth factors

including the neurotransmitters dopamine

The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway

and alterations in the expression of their genes are thought to contribute to neoplastic transformation

• Maximum up to 4000rpm Speed can be set in RPM/RCF

p53 Polyclonal Antibody, 20ul[BT-AP06818] 3D Culture Erb-b2 receptor tyrosine kinase 2TP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.