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ATG4a Rabbit Polyclonal Antibody, 20ul Protein Post-translational Modification The encoded nuclear protein represses

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ATG4a Rabbit Polyclonal Antibody, 20ul Protein Post-translational Modification The encoded nuclear protein repressesAutophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene

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Description

The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells

It also interacts with other transcription factors

Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability

The YTH domain is typical for the eukaryotes and is particularly abundant in plants

This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins| including proteins that are associated with neurodegenerative and metabolic disease

ATG4a Rabbit Polyclonal Antibody, 20ul Protein Post-translational Modification The encoded nuclear protein repressesAutophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene

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