SPTLC1 Polyclonal Antibody, 100ul Enzymes |PTM:Activated by autolytic cleavage after

|PTM:Activated by autolytic cleavage after Lys-97

Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy

Several transcript variants encoding different isoforms have been found for CHEK2

They are involved in the hydrolysis of a variety of peptide and protein substrates

and a single intracytoplasmic catalytic domain

SPTLC1 Polyclonal Antibody, 100ul Enzymes |PTM:Activated by autolytic cleavage afterSPTLC1 encodes a member of the class II pyridoxal phosphate dependent aminotransferase family. The serine palmitoyltransferase long chain base subunit 1 is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L serine and palmitoyl CoA to 3 oxosphinganine with pyridoxal 5' phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary