P53 (Mono Methyl Lys370) Monoclonal Antibody(Q59), 100ul sgRNA Oligos Alternate use of an in-frame

Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon| and a downstream AUG codon| results in two isoforms

|Belongs to the type IV collagen family

The activity of this protein

The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding

It seems to play a major role in endocrine and cardiovascular systems

P53 (Mono Methyl Lys370) Monoclonal Antibody(Q59), 100ul sgRNA Oligos Alternate use of an in-frameThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.