CD57 Polyclonal Antibody, 20ul[BT-AP02069] Cell Culture & Maintenance Alternative splicing of this gene

Alternative splicing of this gene generates 2 transcript variants

BCL6 is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL)

This gene is part of a cluster of similar genes on chromosome 3

The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis

The tilted bottleneck facilitates easy access of pipets and cell scrapers

CD57 Polyclonal Antibody, 20ul[BT-AP02069] Cell Culture & Maintenance Alternative splicing of this geneCOL17A1 (collagen type XVII alpha 1 chain) encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in COL17A1 are associated with both generalized atrophic benign and junctional epidermolysis