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TTF-1(Phospho-Ser327) Rabbit Polyclonal Antibody, 50ul Cell Culture discoidin/neuropilin- and fibrinogen-like domains

SKU: 17573470426

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SEK185.00 SEK217.00

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TTF-1(Phospho-Ser327) Rabbit Polyclonal Antibody, 50ul Cell Culture discoidin/neuropilin- and fibrinogen-like domainsThis gene encodes a protein initially identified as a thyroid specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea choreoathetosis congenital hypothyroidism and neonatal respiratory distress and

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Description

discoidin/neuropilin- and fibrinogen-like domains

The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains

The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon

Defects in this gene or the SMN1 gene can cause spinal muscular atrophy

as anti-viral effect is not dependent on deaminase activity

TTF-1(Phospho-Ser327) Rabbit Polyclonal Antibody, 50ul Cell Culture discoidin/neuropilin- and fibrinogen-like domainsThis gene encodes a protein initially identified as a thyroid specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea choreoathetosis congenital hypothyroidism and neonatal respiratory distress and

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