GPR41 Polyclonal Antibody, 50ul Enzyme Activity Assays This protein is located in

This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA

Fusion of ATF1 and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma

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Several alternatively spliced transcript variants have been found for ATF2

Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer

GPR41 Polyclonal Antibody, 50ul Enzyme Activity Assays This protein is located inReceptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5 trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1 2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin sensitive G(i o) alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.