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RCC1 Polyclonal Antibody, 50ul Vortex Mixer in cells undergoing apoptosis

SKU: 18060244040

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DKK162.00 DKK210.00

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RCC1 Polyclonal Antibody, 50ul Vortex Mixer in cells undergoing apoptosisThe Ras family small GTPase Ran is involved in nuclear envelope formation, assembly of the mitotic spindle and nuclear transport. Like other small GTPases, Ran is active in its GTP bound form and inactive in its GDP bound form. Nuclear RanGTP concentration is maintained through nuclear localization of guanine nucleotide exchange factor (GEF) activity, which catalyzes the exchange of bound GDP for GTP. RCC1 (regulator of chromatin condensation 1) is

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Description

in cells undergoing apoptosis

and is regulated by the NURD nucleosome remodeling and histone deacetylase complex

In the autosomal dominant form

Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS| also known as Gracile Bone Dysplasia)| both characterized by short stature| hypoparathyroidism| bone development abnormalities| and hypocalcemia

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RCC1 Polyclonal Antibody, 50ul Vortex Mixer in cells undergoing apoptosisThe Ras family small GTPase Ran is involved in nuclear envelope formation, assembly of the mitotic spindle and nuclear transport. Like other small GTPases, Ran is active in its GTP bound form and inactive in its GDP bound form. Nuclear RanGTP concentration is maintained through nuclear localization of guanine nucleotide exchange factor (GEF) activity, which catalyzes the exchange of bound GDP for GTP. RCC1 (regulator of chromatin condensation 1) is

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