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PD-ECGF Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection Continual translation of the mRNA

SKU: 18684247416

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PD-ECGF Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection Continual translation of the mRNATYMP encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified.

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Description

Continual translation of the mRNA under conditions of eukaryotic translation initiation factor 2A inactivation is thought to create a feedback loop for reactivation of the gene during recovery from stress

and inhibiting its expression partially suppresses p53-induced apoptosis

Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium

which are both disorders of the peripheral nervous system

Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency

PD-ECGF Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection Continual translation of the mRNATYMP encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified.

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