EKLF/CKLF/UKLF Polyclonal Antibody, 50ul Aspirating Pipets Mutations in this gene are

Mutations in this gene are associated with mental retardation

May be involved in iron metabolism

The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family

May regulate transepithelial ammonia secretion

More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases

EKLF/CKLF/UKLF Polyclonal Antibody, 50ul Aspirating Pipets Mutations in this gene areKLF1 encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in KLF1 result in the dominant In (Lu) blood phenotype.