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This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons

subcellular location:Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle

They may thus play an important role during growth and development

and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease

mGluR7 Polyclonal Antibody, 50ul Roller Bottles Take charge of your experimentsL glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors that have been divided into three groups on the basis of sequence homology,