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Eps15(Phospho Tyr849) Polyclonal Antibody, 20ul Immune Cell Preparation The NKX family of homeodomain

SKU: 19248096193

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Eps15(Phospho Tyr849) Polyclonal Antibody, 20ul Immune Cell Preparation The NKX family of homeodomainThis gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin coated pits and is involved in receptor mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX ALL MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Description

The NKX family of homeodomain proteins controls numerous developmental processes

The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex| which| along with TFIID| is required for efficient activation by SP1

Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis

and circadian rhythm

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Eps15(Phospho Tyr849) Polyclonal Antibody, 20ul Immune Cell Preparation The NKX family of homeodomainThis gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin coated pits and is involved in receptor mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX ALL MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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