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Rb(Phospho Thr821) Polyclonal Antibody, 100ul Adenovirus Packaging This gene encodes an orphan

SKU: 19682645584

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Rb(Phospho Thr821) Polyclonal Antibody, 100ul Adenovirus Packaging This gene encodes an orphanThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family

The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates

Members of this superfamily are characterized by a signature 7-transmembrane domain motif

neurophysin 2 and copeptin

The encoded protein (SWI/SNF related

Rb(Phospho Thr821) Polyclonal Antibody, 100ul Adenovirus Packaging This gene encodes an orphanThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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