VATO Rabbit Polyclonal Antibody, 100ul Biomatrix The encoded protein can be

The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs)

both of which are key extracellular regulators of osteoclast development

Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome

owing to fast inactivation

and leumorphin

VATO Rabbit Polyclonal Antibody, 100ul Biomatrix The encoded protein can beThis gene encodes a portion of the V0 domain of vacuolar ATPase (V ATPase) a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Activity of this enzyme is necessary for such varied processes as protein sorting zymogen activation receptor mediated endocytosis and synaptic vesicle proton gradient generation. Alternative splicing results in multiple transcript variants.