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WNK4 Polyclonal Antibody, 100ul Cellular Cultivation & Health Management It contains a 5' CpG

SKU: 20424528106

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WNK4 Polyclonal Antibody, 100ul Cellular Cultivation & Health Management It contains a 5' CpGThis gene encodes a member of the WNK family of serine threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.

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Description

It contains a 5' CpG island that may be a frequent target of hypermethylation| and it may undergo hypermethylation-based silencing in some bladder cancers

which is necessary for homodimerization and for interaction with other leucine zipper proteins

inducing leukocyte migration and activation

MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al

which is an essential step in neurogenesis

WNK4 Polyclonal Antibody, 100ul Cellular Cultivation & Health Management It contains a 5' CpGThis gene encodes a member of the WNK family of serine threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.

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