EP400 Rabbit Polyclonal Antibody, 20ul Metabolic enzymes A pathogenic role for this

A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes

The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines

the interaction prevents processing of p105 to p50

Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis

This gene belongs to the T-box family of genes

EP400 Rabbit Polyclonal Antibody, 20ul Metabolic enzymes A pathogenic role for this