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DGAT2 Polyclonal Antibody, 100ul Protein Post-translational Modification The calpains| calcium-activated neutral proteases|

SKU: 20500744657

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DGAT2 Polyclonal Antibody, 100ul Protein Post-translational Modification The calpains| calcium-activated neutral proteases|This gene encodes one of two enzymes which catalyzes the final reaction in the synthesis of triglycerides in which diacylglycerol is covalently bound to long chain fatty acyl CoAs. The encoded protein catalyzes this reaction at low concentrations of magnesium chloride while the other enzyme has high activity at high concentrations of magnesium chloride. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

The calpains| calcium-activated neutral proteases| are nonlysosomal| intracellular cysteine proteases

an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract

Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration

Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported

The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2

DGAT2 Polyclonal Antibody, 100ul Protein Post-translational Modification The calpains| calcium-activated neutral proteases|This gene encodes one of two enzymes which catalyzes the final reaction in the synthesis of triglycerides in which diacylglycerol is covalently bound to long chain fatty acyl CoAs. The encoded protein catalyzes this reaction at low concentrations of magnesium chloride while the other enzyme has high activity at high concentrations of magnesium chloride. Multiple transcript variants encoding different isoforms have been found for this gene.

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