IL-8RBeta Polyclonal Antibody, 100ul[BT-AP04519] Cell Senescence Human cell lines lacking a

Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage

and is overexpressed in hematopoietic malignancies and in prostate cancer

and its expression and activation is associated with transformation and tumorigenesis

Most abundant in adult thymus and fetal liver

This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex

IL-8RBeta Polyclonal Antibody, 100ul[BT-AP04519] Cell Senescence Human cell lines lacking aC X C chemokine receptor type 2 encoded by CXCR2 is a member of the G protein coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G protein activated second messenger system. This receptor also binds to chemokine (C X C motif) ligand 1 (CXCL1 MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for