Na+ CP type IX Alpha Polyclonal Antibody, 50ul Mammalian Expression Two alternatively spliced transcript variants

Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections

This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE)| a key enzyme in the phototransduction cascade

neuronal cells

The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex

Na+ CP type IX Alpha Polyclonal Antibody, 50ul Mammalian Expression Two alternatively spliced transcript variantsSCN9A encodes a voltage gated sodium channel which plays a significant role in nociception signaling. Mutations in SCN9A have been associated with primary erythermalgia, channelopathy associated insensitivity to pain, and paroxysmal extreme pain disorder.