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Rat Myelin Associated Glycoprotein, MAG ELISA Kit, 96T Yeast Expression Together these subunits are composed

SKU: 20971415628

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Rat Myelin Associated Glycoprotein, MAG ELISA Kit, 96T Yeast Expression Together these subunits are composedAdhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (PubMed: 8995428, PubMed: 9298990). Not required for initial myelination, but seems to play a role in the maintenance of normal axon myelination. Protects motoneurons against apoptosis, also after injury; protection against apoptosis is probably mediated via interaction

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Description

Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins

Bactericidal C-type lectin (By similarity)

PTM:Serine or threonine phosphorylation within the basic region may regulate neurogenic activity

The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development

Phosphorylates CLOCK AT 'Ser-427' and targets it for proteasomal degradation (PubMed: 19946213)

Rat Myelin Associated Glycoprotein, MAG ELISA Kit, 96T Yeast Expression Together these subunits are composedAdhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (PubMed: 8995428, PubMed: 9298990). Not required for initial myelination, but seems to play a role in the maintenance of normal axon myelination. Protects motoneurons against apoptosis, also after injury; protection against apoptosis is probably mediated via interaction

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