Tie-2(Phospho Tyr1108) Polyclonal Antibody, 20ul ADME which contains one PH domain

which contains one PH domain and one SH2 domain

Reciprocal translocations between chromosomes 17 and 22| where this gene and the gene for platelet-derived growth factor beta are located| are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans| resulting from unregulated expression of the growth factor

which is a recessive X-linked disorder

The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein

The encoded protein is a component of the multisubunit transport protein particle (TRAPP) complex

Tie-2(Phospho Tyr1108) Polyclonal Antibody, 20ul ADME which contains one PH domainThis gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin like domains, three epidermal growth factor (EGF) like domains and three fibronectin type III repeats. The ligand angiopoietin 1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated